The Use of the RAFT-Technique for the Preparation of Temperature/pH Sensitive Polymers in Different Architectures.

Licea-Claverie, A.; Alvarez-Sanchez, J.; Picos-Corrales, L.A.; Obeso-Vera, C.; Flores, M.C.; Cornejo-Bravo, J.M.; Hawker, C.J.; Frank, C.W.;
Macromolecular Symposium,
2009
283-84, 56-66.

In this contribution we report the use of the RAFT-technique for the preparation of three types of responsive polymeric materials with a high potential of application in the biomedical field: 1.-Diblock copolymers with reversible self-assembly capacity as a function of pH based on N,N′-diethylaminoethyl methacrylate (DEAEM) and 2-methacryloyloxy benzoic acid (MAOB); 2.-Diblock copolymers with reversible self-assembly capacity as a function of temperature, based N-isopropylacrylamide (NIPAAm) and n-hexyl acrylate (HA); and 3.-Polymeric stars with random number of arms consisting either in NIPAAm-arms or copolymeric NIPAAm-arms and hydrophobic core.